Namenda (memantine) is primarily used to treat moderate to severe dementia of the Alzheimer’s type. It is not a cure for Alzheimer’s disease but helps manage symptoms and may slow the progression of the disease in some patients.
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Common use
Namenda is used to treat moderate to severe dementia of the Alzheimer's type. Namenda's mechanism of action is to help balance a brain chemical called glutamate. In Alzheimer's, there can be too much glutamate activity, which can harm brain cells. By controlling glutamate, Namenda may help protect brain cells from damage and improve memory and thinking skills in some people with Alzheimer's.
Dosage and direction
Namenda is usually taken once or twice daily. Namenda can be taken with or without food. Do not crush, chew, break, or open an capsule. Swallow it whole. Initial dose: Namenda 5 mg orally once a day, then titrated upwards by 5 mg per week. Maintenance dose: Namenda 5 mg once a day up to Namenda 10 mg twice a day. Maximum dose: 20 mg per day.
Precautions
Before taking Namenda, tell your doctor about all your medical conditions including if you have: have or have had seizures or epilepsy; have liver disease; have kidney disease; have problems passing urine; have a bladder or kidney infection; are pregnant or plan to become pregnant; are breastfeeding or plan to breastfeed.
Contraindications
Do not take Namenda if you are allergic to memantine, Namenda, or any of the inactive ingredients in the tablets.
Possible side effect
The most common Namenda side effects are: dizziness; headache; confusion; constipation.
Drug interaction
Tell your doctor about all your current medicines and any you start or stop using, especially: amantadine; ketamine; zonisamide; cough medicine that contains dextromethorphan (Delsym, Robitussin Maximum Strength, Vicks 44, and others); medicines to make the urine alkaline - urine sodium bicarbonate, potassium citrate (K-Lyte, Urocit-K), sodium citrate and citric acid (Bicitra, Oracit), or sodium citrate and potassium (Citrolith, Polycitra) (can reduce the clearance of Namenda by about 80%); medicine to treat glaucoma or increased pressure inside the eyes - acetazolamide, methazolamide.
Missed dose
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up for the missed dose.
Overdose
Seek emergency medical attention.
Storage
Store Namenda at room temperature between 59°F to 77°F (15°C to 30°C) away from moisture and heat. Keep away from children and pets.
