Sulbutiamine (other name Arcalion)

Common use

Arcalion is primarily used for managing a condition known as asthenia, which is characterized by a lack of energy or weakness. This medicine is a member of the class of medicines that are synthetic derivatives of vitamin B1, or thiamine. This medicine can also be used to manage fatigue and as an adjunct therapy for Alzheimer's disease.

Dosage and direction

Always take the tablet whole. Do not crush or chew it. Use a full glass of water to swallow the tablet. The medicine should be taken split between breakfast and lunch. Usually, it's not advised to take Arcalion tablet for more than 4 weeks.

Precautions

Before you begin taking this medicine, it's important to consult your doctor about the right dosage and frequency. You should also inform your doctor about any pre-existing conditions or ongoing medications you are taking.

Contraindications

Arcalion tablet should not be taken if you have known hypersensitivity to sulbutiamine or any other excipients in the medicine.
Metabolic Disorders: If you have conditions like galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption, you should avoid taking Arcalion. It might exacerbate these conditions.
Psychiatric Disorders: People with bipolar disorder should use caution when taking Arcalion due to its potential for abuse.

Possible side effect

Arcalion tablet may cause the following side effects: Nausea; Vomiting; Stomach pain; Diarrhea; Anxiety; Tremor; Insomnia; Skin rash; Asthenia.

Drug interaction

Diuretics: Medicines like furosemide and hydrochlorothiazide can interact with Arcalion. This interaction might increase the loss of thiamine through urine, which could reduce the effectiveness of Arcalion.
Neuromuscular Blocking Agents: Medications such as rocuronium and vecuronium might interact with Arcalion. This is because sulbutiamine, the active ingredient in Arcalion, can enhance their effects.

Missed dose

If you've missed a dose of Arcalion, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never increase your dosage without consulting your doctor.

Overdose

In case of an overdose of Arcalion, you may experience symptoms like heightened anxiety, irritability, or tremors. If such symptoms persist or worsen, it's crucial to inform your doctor.

Storage

Store Arcalion tablet at room temperature, ideally below 30°C. Keep the product in a dry place, away from direct sunlight and moisture. It's important to keep this medication out of reach of children.